An I/O line called „digital pot“ likely is the chip select line for an external chip with SPI interface.
SPI is a bus. You can connect any number of devices to it. Which one you are talking to, depends on which one gets its chip select (CS) input low. All others remain passive. So if you pull this line low (and all others like the one for the CC3000 high), you can talk to the pot through SPI. But how to program the POT (and whether there is one at all) depends on your application. See the schematics of your PCB and the device datasheet (of the POT) for details.